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oddly this got no press at all: $577 million dollars allocated for pandemic preparedness therapeutics research


The NIH has established nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern. It's not specifically for COVID-19 and there is no vaccine research, just therapeutics. The antivirals will target specific viral families with high potential to cause a pandemic in the future. These include paramyxoviruses, bunyaviruses, togaviruses, filoviruses (including Ebola viruses and Marburg virus), picornaviruses (including enteroviruses and other cold-causing viruses), and flaviviruses (including the viruses that cause yellow fever, dengue and Zika).

The objective is to find new classes of antiviral drugs with the potential to curb future epidemics before they can become widespread. So... there is a local outbreak. You send the drug there and stop it in its tracks and nobody in the general public even realizes the bullet that was dodged.

One special emphasis is to target entirely new mechanisms for intervention, some that might be broad-spectrum antivirals. For instance, targeting the viral-specific enzymes that unwind DNA or RNA hairpins to make replication possible. Each of the 9 centers is actually a consortium of dozens of professors, typically doing research in multiple large universities, research institutes, medical schools, and research hospitals. All centers have already established ties to pharmaceutical companies that will advise and progress compounds to trials.

This has, in my opinion, been the most forward-thinking expenditure that has yet emerged as a consequence of the pandemic.

The continuation of funding will be merit-based and milestone driven. Any centers not performing will be canned. Top performers will be funded beyond the initial 3 years.

Woodson on TJD Coming Back

“I’m hoping like hell he comes back, because he’s a big piece to the puzzle.”

IU@Iowa, Game 2: Iowa 12 IU 0. IU gets thumped in a total team effort...

RHP Jack Perkins is on the mound for IU with an ERA of 4.75 in 72 IP and an OBA of .217, while RHP Dylan Nedved is on the mound for Iowa with an ERA of 3.90 in 57.2 IP and an OBA of .198.

In games that are in progress as I post this Purdue trails MD 7-5 in the 6th. Ill and PSU are tied at 1-1 in the 4th, while Neb and MSU are just getting started was well as NU and Minn.

In IU's 1st, Whalen strikes out to lead off. Jessee walks on four pitches to put a runner on and one out. Pyne strikes out looking for two outs. Mathison flies out to end IU's 1st.

In Iowa's 1st, the leadoff hitter reached on an infield hit after the ball took a weird bounce that Glasser couldn't field quick enough to get the runner. Here we go again as the next batter gets a single to put runners on the corners and no outs. IU gets a DP but the runner on 3rd scores. A two-out double puts a runner in scoring position with two outs. Perkins then walks a man to put runners on 1st and 2nd with two outs. Perkins gets out of the inning with a K looking. Tucker had a shaky 1st yesterday and settled down, so hopefully Perkins can do the same since we need him to go deep into the game today.

Poor Loser Trump -- loses again


Of course, Trump never wanted to win this suit -- he just wanted to raise hell and delay things.

He doesn't understand or accept that other people (like judges) have the right to make actual decisions concerning his affairs (unless, of course, they already agree with him).

Save America, Republicans!! Vote for Trump!!

(Rebuttal posts that mention "Liberals, "Democrats," Progressives" etc. are going to look stupid, so go ahead and post them !!)

Friday Recruiting Notebook - May 20

The big announcement of Trayce Jackson-Davis returning headlined the news this week.

After it was reported that he tested positive for Covid last week and was out of the NBA Combine, things really shifted towards him returning. Without being able to showcase his skills in a team and individual setting really hurt him.

That completes Indiana’s 2022-23 roster.



The class of 2023 is headlined by two players: power forward Arrinten Page and hybrid forward TJ Power.

At this point, both players are expected to visit Indiana this summer.

As for Power, he spoke to Indiana head coach Mike Woodson recently and it was really the first chance he had to get to know Woodson. He told TheHoosier.com about his conversation:

"It was just cool to hear from the head coach for sure that always solidifies the interest in my mind. He touched on getting out to see campus and just starting a relationship. I was impressed with his vision for building a winning culture again at Indiana."

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As for another class of 2023 prospect that Indiana is active on, Andrej Stojakovic told Rivals national analyst Travis Graf that he plans on taking the following visits: Texas, Virginia, Tennessee, and either UConn or IU before July 31st. He has one visit set to Stanford.

He also added UCLA, USC, Kansas, Kentucky, and UConn or IU in the fall.

Now, I don't expect him to take all of those visits. That is A LOT of travel. But, Indiana should get a visit.

The teams in the second list seem to be the strongest here and Kentucky was a big offer for him.

If Indiana wants a solid chance in this recruitment, it needs to push for a visit this summer.

Time will tell and more programs will jump in. I wouldn't expect him to make any type of early decision.
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The Adidas May Classic took place last weekend and TheHoosier.com was in attendance. It wasn't a great day of scouting with some major lack of competition but nonetheless, here were the scouting notes from Kyler.

Flory Bidunga – Relatively easy day for Bidunga here as there was no player in any game that could match up to him skill or size wise. Anytime he received the ball in the post, it was going in. Pick-and-roll game was money for him. Did struggle a little bit leading a fastbreak as nearly every time he did, it resulted in a turnover. Still is obviously learning the game but was not a day where mistakes would hurt his team.

Raleigh Burgess – Played with a high motor yet again on both ends of the floor. Offensively, he was real aggressive at attacking the basket but struggled shooting from the perimeter. Starting to notice how well him and Cooper Koch play off one another as they look to have built a strong chemistry where both can rotate inside and out on the offense. If Burgess can start to show consistency from the wing, he can be that true stretch four at the high major level.

Cooper Koch – Like most of his teammates, Koch also had a relatively easier day when it came to the offensive end of the floor. Thought he did a tremendous job getting wide in transition and taking advantage of the open look from the perimeter. Looks to me he is starting to play at a more fluid pace than what I saw a few weeks ago. More of a perimeter player than a true post but can really light it up from deep with his smooth shooting mechanics.

JQ Roberts – Roberts once again played at a fast pace and showed a ton of confidence in his overall game. Played mostly above the rim like her normally does however, would have liked to have seen more of his perimeter game as this was the type of contest for him to work on showcasing that. Sticking with the perimeter, felt like he showed more of that during the high school season than as of late. Nonetheless, Roberts had a solid day here on both ends.

Big Ten Note: Was able to see the future backcourt of Penn State with Logan Imes and Braeden Shrewsberry play for the first time this season. Both have incredible backcourt chemistry and play so well off one another. Both can shoot it well from deep and make plays on the ball. Has a chance to be one of the better backcourts in the Big Ten around their junior or senior year.

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Small note

Devonte Green and Josh Newkirk have been the two Indiana players announced as joining the Indiana TBT team this season.

Mike Woodson spoke at the Big Brothers and Big Sisters charity event earlier this week. This is what he had to say:

IU@Iowa, Game 1: Iowa 30 IU 16. IU blows big lead and gets drubbed in an absolutely embarrassing fashion...

RHP Braydon Tucker is on the mound with an ERA of 6.25 in 40.1 IP, while RHP Adam Mazur is on the mound for Iowa with a stingy ERA of 2.18 and a WHIP of just 0.837 in 86.2 IP, and his numbers are even better in recent games.

On a side note, both PSU and Purdue are losing big right now to Illinois and MD, respectively, as I post this.

In the T1st, Whalen leads off with a walk. Jessee then shocks the Iowa crowd with a two-run homer down the RF line on a pitcher that just doesn't give up runs like this. Mathison then doubles to put a runner in scoring position with no outs. Pyne strikes out for the first out and the runner still on 2nd. Glasser then hits a two-run homer to make it 4-0 against the B1G's top pitcher in many categories. There's wind blowing out at about 20 mph today. Ellis grounds out for two outs and no one on. Tibbetts flies out to end a highly productive first inning for IU.

In the B1st, Tucker really struggles in the 1st to find the plate and when we he wasn't throwing balls and giving up a WP which scored a run, he was giving up base hits as Iowa cuts into the lead at 4-2 with runners on 1 and 2nd and one out. Tucker gets a K for the 2nd out with runners still on 1st and 2nd. Tucker then ends the inning on a K and it could have been worse, but Tucker seemed to settle down to limit the damage.
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