Would create similar issues to what we've had in his first 3 seasons...2 really, really good bigs...with neither versatile enough to guard and rebound effectively away from the basket. And then as you referenced, the continued gravity to clog the lane with 2 guys that are post centric offensively.
Surround them with 3 elite guards, that can shoot, score, and defend like heck on both ends of the floor...sure, that probably works well. But start adding guys like Mack, Tucker, Gallo to play alongside them, and the weaknesses start to get exposed and amplified big time.
I'd rather have Williams or Payne, if they'd play a "6th man" role with Mack and Malik starting, and work, like crazy, to get elite and versatile perimeter players.