They won't. They're college kids. This is one of the most overused excuses in the book at the college level.
I know people roll their eyes when people talk about their own playing days on here...but it applies in this situation.
I played small college basketball. We played roughly 35 games a year. My junior and senior year I averaged about 36-37 minutes of playing time a game. We didn't have nutritionists (we ate Papa Johns and Pizza King after our games), we didn't have doctors, we had a training staff, but they didn't dote on us and care for us, they taped our ankles and gave us ice packs when we asked, we drove to ALL our away games, in a 15 passenger van...
Kids at IU are better athletes to start with, they get world class medical treatment whenever they need it, they have nutritionists, they have strength and conditioning coaches, they get massages after every practice and game, and none of them hardly ever play more than 35 minutes in a game...that has 8 TV timeouts...
And I never, not once, felt run down or overly fatigued.
This isn't a thing in college basketball. It just isn't.