My uninformed speculation is that he was already hurt. Maybe his back... He wasn't stepping up into the pocket, or stepping into his throws. While he does that sometimes, it's not usually over and over. He also wasn't pulling the ball down on the read option, and the unblocked end was stuffing the play.
As a result, we went wildcat and enticed them to take a guy out of the box. It was funny, one time no one went with Penix in motion, so he was open out there, and Scott literally pointed at Penix until a Maryland backer ran out there to cover him. Then we ran, and got a chunk. After that, I figured they'd have to stop covering Penix, since it was obvious we weren't going to throw it to Penix.
Remember against PSU we ran several designed QB draws? We aren't doing any of that anymore, and it's probably because they know he's nicked up. With a balky back, it can come and go--and you can look fine one minute and not the next.