COVID-19 for Dummies

Discussion in 'The Water Cooler' started by CO. Hoosier, Mar 29, 2020.

  1. CO. Hoosier

    CO. Hoosier Hall of Famer
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    COVID-19 From an Asst. Prof in infectious diseases at Johns Hopkins University,



    * The virus is not a living organism, but a protein molecule (DNA) covered by a protective layer of lipid (fat), which, when absorbed by the cells of the ocular, nasal or buccal mucosa, changes their genetic code. (mutation) and convert them into aggressor and multiplier cells.
    * Since the virus is not a living organism but a protein molecule, it is not killed, but decays on its own. The disintegration time depends on the temperature, humidity and type of material where it lies.
    * The virus is very fragile; the only thing that protects it is a thin outer layer of fat. That is why any soap or detergent is the best remedy, because the foam CUTS the FAT (that is why you have to rub so much: for 20 seconds or more, to make a lot of foam). By dissolving the fat layer, the protein molecule disperses and breaks down on its own.
    * HEAT melts fat; this is why it is so good to use water above 25 degrees Celsius for washing hands, clothes and everything. In addition, hot water makes more foam and that makes it even more useful.
    * Alcohol or any mixture with alcohol over 65% DISSOLVES ANY FAT, especially the external lipid layer of the virus.
    * Any mix with 1 part bleach and 5 parts water directly dissolves the protein, breaks it down from the inside.
    * Oxygenated water helps long after soap, alcohol and chlorine, because peroxide dissolves the virus protein, but you have to use it pure and it hurts your skin.
    * NO BACTERICIDE SERVES. The virus is not a living organism like bacteria; they cannot kill what is not alive with antibiotics, but quickly disintegrate its structure with everything said.
    * NEVER shake used or unused clothing, sheets or cloth. While it is glued to a porous surface, it is very inert and disintegrates only between 3 hours (fabric and porous), 4 hours (copper, because it is naturally antiseptic; and wood, because it removes all the moisture and does not let it peel off and disintegrates), 24 hours (cardboard), 42 hours (metal) and 72 hours (plastic). But if you shake it or use a feather duster, the virus molecules float in the air for up to 3 hours, and can lodge in your nose.
    * The virus molecules remain very stable in external cold, or artificial as air conditioners in houses and cars. They also need moisture to stay stable, and especially darkness. Therefore, dehumidified, dry, warm and bright environments will degrade it faster.
    * UV LIGHT on any object that may contain it breaks down the virus protein. For example, to disinfect and reuse a mask is perfect. Be careful, it also breaks down collagen (which is protein) in the skin, eventually causing wrinkles and skin cancer.
    * The virus CANNOT go through healthy skin.
    * Vinegar is NOT useful because it does not break down the protective layer of fat.
    * NO SPIRITS, NOR VODKA, serve. The strongest vodka is 40% alcohol, and you need 65%.
    * LISTERINE IF IT SERVES! It is 65% alcohol.
    * The more confined the space, the more concentration of the virus there can be. The more open or naturally ventilated, the less.
    * This is super said, but you have to wash your hands before and after touching mucosa, food, locks, knobs, switches, remote control, cell phone, watches, computers, desks, TV, etc. And when using the bathroom.
    * You have to HUMIDIFY HANDS DRY from so much washing them, because the molecules can hide in the micro cracks. The thicker the moisturizer, the better. * Also keep your NAILS SHORT so that the virus does not hide there.
     
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  2. iuwclurker

    iuwclurker All-Big Ten
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    The Alcohol has to be under 90% as well, otherwise it evaporates too quickly to affect the virus.
     
  3. twenty02

    twenty02 Hall of Famer
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    Sounds like being on a boat in the Caribbean with a few cases of 151 should keep me safe for a good while.
     
  4. JamieDimonsBalls

    JamieDimonsBalls All-Big Ten
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    Looks like the Chinese are back to their uncivilized behavior

     
  5. 76-1

    76-1 All-American
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    What a surprise... DWS

    Spain and the Netherlands both just found out what their new Chinese "friends" are all about. The Spanish received test kits that were only 30% accurate and the Dutch received masks that were unusable...

    We have to get our pharmaceutical production moved back to the U.S. yesterday!!!
     
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  6. INRanger27

    INRanger27 All-American
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    That will serve
     
  7. Cream&Crimson

    Cream&Crimson All-Big Ten
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    If you could acquire a bottle or two of 151, you'd be golden. That's actually the right concentration of alcohol.
     
  8. JamieDimonsBalls

    JamieDimonsBalls All-Big Ten
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  9. twenty02

    twenty02 Hall of Famer
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    What a shocker. Hopefully this will be a turning point, and force the world to address the biggest threat to human rights existence on the planet.
     
  10. Sope Creek

    Sope Creek Hall of Famer
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    Good post, CO.

    I was interested in the protective layer of fat information . . . I read recently where there seems to be a risk factor of obesity in relation to those who require intensive care treatment for the coronavirus. Your information about the protective layer of fat seems to correlate well with the obesity risk factor. As noted in this NY Post article (https://nypost.com/2020/03/26/obesity-increases-risk-for-coronavirus-complications-report/) there are a number of obesity related conditions and effects that may increase the coronavirus risk. But what I'm wondering is whether the extra fat that an obese person has may offer added protection for the virus protein per se.
     
  11. iuwclurker

    iuwclurker All-Big Ten
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    Yes, that does raise interesting questions. If the coronavirus can only replicate inside a cell then presumably there must be fat there available in that cell for it to take on as its exterior surface. So if there is less fat available does that make it harder for the virus to replicate in quantity?
     
  12. outside shooter

    outside shooter Hall of Famer
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    The virus is studded with nonpolar (greasy) proteins called spike proteins, which bind to, and activate, a protein on the surface of human cells called ACE2. Once activated, ACE2 causes the cell to internalize (engulf) the material to which it is attached, by activating enzymes. Once internalized, the virus releases it's RNA, which enters the nucleus and ultimately scrambles with human RNA to encode for DNA that will be transcribed and make huge numbers of copies of the virus, including its entire genome.

    The points of possible intervention include:
    1) blocking the interaction of ACE2 and the spike protein, by binding a molecule to one or the other and destroying their shape complimentarity, like adding sand into the gears.
    2) blocking the enzymes that are activated by ACE2 that cause the virus to be internalized
    3) blocking the viral RNA itself, once engulfed, by binding to it and preventing its transcription.
    4) finding a molecule that impedes any step in the process. There are likely other transporters or enzymes involved.
    5) provoking a immune response (vaccine) by generating antibodies to recognize and destroy the virus by recognizing the amino acid sequence of the spike protein.

    #5 is a multipronged option, as there are at least 6 types of vaccines, with differing efficacies that vary by disease: inactivated virus (e.g., seasonal flu vaccines), attenuated virus (Measles vaccine), recombinant protein (Hepatitus B vaccine) , DNA vaccine (Equine West Nile virus), mRNA vaccine (no approved examples, yet), and recombinant vector vaccines (ebola vaccine, limited efficacy).
     
    12 outside shooter, Mar 30, 2020
    Last edited: Mar 30, 2020
  13. Cream&Crimson

    Cream&Crimson All-Big Ten
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    Researchers in Poland claim to have identified the enzyme that if inhibited, will kill the virus, and they claim to have identified a "key" to doing that.

    I saw a report on this a few weeks ago, but there doesn't seem to be much press on it. But it sounds encouraging.

    Link

    Edit: better, more descriptive source
     
  14. Sope Creek

    Sope Creek Hall of Famer
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    'We have not patented this. The publication preprint is available online. This is a gift from my laboratory to anyone interested'.
     
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  15. iuwclurker

    iuwclurker All-Big Ten
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    Wow! Mouthful. Thanks!


    Where does the “fat outer lining” fit into that picture? Is “fat” a misnomer for the spike proteins? In other words, what is it that the hot water and soap “dissolve”? And if that’s not the spike proteins, when does it become part of the genesis and where does it come from?
     
  16. Sope Creek

    Sope Creek Hall of Famer
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    You forgot the "greasy" part of the description . . . that ought to tell you where the fat is.
     
  17. outside shooter

    outside shooter Hall of Famer
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    A phospholipid membrane layer coats the virus particles. This can be disrupted by soaps. The spike proteins are hydrophobic ("water fearing") molecules that essentially float along, within the lipid membrane. If the membrane is disrupted, the spike proteins are released, dispersed, and there is no way for the virus's RNA to be internalized.
     
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  18. iuwclurker

    iuwclurker All-Big Ten
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    Lol. I noted greasy and asked for more detail...
     
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  19. iuwclurker

    iuwclurker All-Big Ten
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    Thanks again.


    Hm... so I’m wondering if attacking the virus outer membrane is an option, inside the body. It seems all cell membranes contain phospholipids. True? How come soaps affect the virus outer layer but not our skin, for example? Is that what the “dead” layer of skin does, protect the inner layers’ phospholipid membranes?
     
  20. outside shooter

    outside shooter Hall of Famer
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    All cell membranes contain phospholipids, but human cells have many more proteins embedded in them which interact with one another and greatly stabilize the membrane. A virus genome codes for far fewer proteins and their outer membrane is relatively much more barren and much less cohesive.
     
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  21. NPT

    NPT Moderator
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    Here's an interesting read.
     
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  22. iuwclurker

    iuwclurker All-Big Ten
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    Man, each cell is freaking loaded with all kinds of chemicals. No wonder bodies get screwed up, or not.
     
  23. outside shooter

    outside shooter Hall of Famer
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    an inspiring image for the history books

    [​IMG]
     
  24. Cream&Crimson

    Cream&Crimson All-Big Ten
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    Wow. That's poignant.
     
  25. INRanger27

    INRanger27 All-American
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    Sorry sir. This is all fake news. Did not come from Johns Hopkins.

    https://www.snopes.com/fact-check/johns-hopkins-covid-summary/
     
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  26. IUCrazy2

    IUCrazy2 Hall of Famer
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    Yes, along with other things.
     
  27. CO. Hoosier

    CO. Hoosier Hall of Famer
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    Hm.

    First I didn't represent it being a publication of JH. And the communication itself doesn't represent it as being a JH statement. Second, I know the Listerene comment was wrong--anybody should. The trivial things Snopes took the time and trouble to question tells me the remainder is accurate, and IMO, important information.
     
  28. INRanger27

    INRanger27 All-American
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    Without proper sourcing and attribution, the list is completely meaningless. Completely.

    Further, Snopes is very clear that they avoided going line by line in their comments.

    Washing hands with 25C water? That’s room temperature water. This is obviously typical terrible social media nonsense. Fake news.
     
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  29. iuwclurker

    iuwclurker All-Big Ten
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    What is your thin-skinned problem? No one accused you of an attribution, though you did:

    “COVID-19 From an Asst. Prof in infectious diseases at Johns Hopkins University,“
    Second, your take-down of Snopes is unwarranted and pathetic. They provide a service AND the proper website link for your COVID 19 For Dummies thread.

    Posting in good faith is simple. You thank Ranger for fact-checking your oversight. You thank Snopes for their due diligence. You post the right link.

    You don’t run and hide.You started the thread. Take some responsibility, guy.
     
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  30. iuwclurker

    iuwclurker All-Big Ten
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  31. CO. Hoosier

    CO. Hoosier Hall of Famer
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    I don't have a thin skin problem. A better question is why the ad hominem . . . . .again?
     
  32. INRanger27

    INRanger27 All-American
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    Simple:
    1. Being an international business guy - I know that 25C ain’t hot
    2. The whole message is written like a typical social media / chain email and I’ve never found any of those to ever be true
    3. Citing an abstract “doctor” or expert without naming the doctor or expert is 99% of the time the alarm klaxon sounding fake news to follow
     
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  33. Marvin the Martian

    Marvin the Martian Hall of Famer
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    Can you imagine if everyone thought that way, it would put hundreds of Russians out of work at troll farms. Oh, and we wouldn't have Trump as president.
     
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  34. iuwclurker

    iuwclurker All-Big Ten
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    Lol. Righto...


    What ad hominem? There is none in my post. Being defensive is known as thin-skinned. That’s an attribution. I’m not insulting you (though a thin-skinned person might construe it as such) I’m calling you out because I know you can do better, if you choose. Why do you dodge rather than address the substance? Should I have taken your cue and responded, “That’s no argument”?

    In short, dodging is cowardly. How does one communicate this to you without you feeling it’s an ad hominem?
     
  35. CO. Hoosier

    CO. Hoosier Hall of Famer
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    Snopes attribution finding is a water is wet comment. Snopes' criticism of the content is either trivial or reflects a difference of opinion.

    BTW, I forwarded it to a microbiologist/RN, an MD and another scientist. Nobody criticized it.

    Each of us can read it for what it's worth.
     
  36. Lucy01

    Lucy01 All-American
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    Screw Rachel Maddow and her false reporting!
     
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  37. JamieDimonsBalls

    JamieDimonsBalls All-Big Ten
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  38. CO. Hoosier

    CO. Hoosier Hall of Famer
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    Hilarious.
     
  39. iuwclurker

    iuwclurker All-Big Ten
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    Also, thick-skinned don’t even notice ad hominems...I couldn’t care less what you call me. I just wade through the bullshit looking for something of substance.

    Tedium in that endeavor also warrants the Ignore button...
     
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  40. mashnut

    mashnut Freshman
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    If you’re going to keep waving your hominem around, you don’t get to whine when we point and laugh.
     
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